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- Recessive: In recessive inheritance, a person needs to have two copies of a gene that both have a mutation and are not working properly in order to be affected. A person who has a mutation in one copy of the gene but not the other are called “carriers,” and do not have CMT or symptoms of CMT. If two carriers have children, there is a 1 in 4 or 25% chance in each pregnancy of having a child affected with CMT. A person with a recessive form of CMT will pass on one copy of the gene with the mutation to each child.
